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BACKGROUND Therapeutic hypothermia has been shown to be of benefit in improving neurological outcome in cardiac arrest. It now is being investigated in acute stroke and myocardial infarction. The majority of the literature describes its use in intubated, pharmacologically paralyzed patients, using surface cooling techniques that are susceptible to patient… (More)
BACKGROUND Using a selective α-blocker for medical expulsive therapy (MET) is a cost-effective treatment approach widely used for ureteral stones. OBJECTIVE To evaluate the efficacy of silodosin, a selective α-1a receptor antagonist, in this setting. DESIGN, SETTING, AND PARTICIPANTS This was a multicenter, phase 2 study conducted in adult patients with… (More)
This multicenter, randomized, crossover, open-label study (ClinicalTrials.gov identifier: NCT01161563) assessed patients'and clinicians'perceptions of injection site tolerability and adverse events following the intramuscular injection of triptorelin pamoate or subcutaneous injection of leuprolide acetate in 107 male, patients with advanced prostate cancer.
A hydrothermal cell with 320 ml internal volume has been designed and constructed for in situ neutron diffraction studies of hydrothermal crystallizations. The cell design adopts a dumbbell configuration assembled with standard commercial stainless steel components and a zero-scattering Ti-Zr alloy sample compartment. The fluid movement and heat transfer… (More)
Introduction Artificial Neural Networks (ANNs) use a different computational paradigm than conventional von Neumann mechanisms. ANNs are composed of nodes and weighted connections between nodes, where each node computes its output based on a function of its weighted inputs. The overall function that a network computes is typically changed by altering the… (More)