Scott M. Hynes

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To develop a population pharmacokinetic model to quantitate the distribution kinetics of glycylsarcosine (GlySar), a substrate of peptide transporter 2 (PEPT2), in blood, CSF and kidney in wild-type and PEPT2 knockout mice. A stepwise compartment modeling approach was performed to describe the concentration profiles of GlySar in blood, CSF, and kidney(More)
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