Scott M. Auerbach

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Vascular endothelial-cadherin (VE-cad) is localized to adherens junctions at endothelial cell borders and forms a complex with alpha-, beta-, gamma-, and p120-catenins (p120). We previously showed that the VE-cad complex disassociates to form short-lived "gaps" during leukocyte transendothelial migration (TEM); however, whether these gaps are required for(More)
Leukocyte recruitment to tissues and organs is an essential component of host defense. The molecular mechanisms controlling this process are complex and remain under active investigation. The combination of biochemical techniques and live cell imaging using in vivo and in vitro flow-model approaches have shed light on several aspects of neutrophil(More)
Vasopressin may be a neurotransmitter and in vivo experiments suggest that it acts on monoamine metabolism. The rat hippocampal slice contains serotonergic nerve terminals but not cell bodies; we studied the effect of vasopressin on the synthesis and release of serotonin from these nerve terminals during depolarization. Incubation of slices in a buffer(More)
We have studied the convergence properties of embedded and constrained cluster models of proton transfer in zeolites. We applied density functional theory to describe clusters and ONIOM to perform the embedding. We focused on converging the reaction energy and barrier of the O(1) to O(4) jump in H-Y zeolite as well as vibrational and structural aspects of(More)
We present a non-destructive, reusable apparatus with which to measure physical adsorption isotherms of intact porous membranes. We developed a two-piece sample container to make reliable sorption measurements of porous membranes, the properties of which may differ from those of powders due to crystal intergrowth. This novel system employs a resealable(More)
We compare the adsorption properties of intact supported silicalite membranes with those of silicalite powder and of alumina supports using nitrogen and argon as adsorbates at 77 K. We disentangle contributions from the membrane and support and find that the support contributes significantly to the total quantity adsorbed due to its relative thickness. The(More)
Nitrogen substituted zeolites with high crystallinity and microporosity are obtained by nitrogen substitution for oxygen in zeolite Y. The substitution reaction is performed under ammonia flow by varying the temperature and reaction time. We examine the effect of aluminum content and charge-compensating cation (H(+)/Na(+)/NH(4)(+)) on the degree of nitrogen(More)