Scott J. Shaffer

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To test the hypothesis that neutralization of polyanions of the glomerular filter in vivo will lead to loss of charge-dependent glomerular permselectivity, we have infused i.v. the polycation hexadimethrine (HDM) into rats. Heavy proteinuria resulted after a lag period of 30 to 50 min, and it resolved when the infusion was stopped. Concurrent administration(More)
A partially purified toxin of Clostridium difficile induced similar morphologic changes in three different tissue-cultured mammalian cell lines. The morphologic changes were not associated with biochemical changes indentical to those caused by the enterotoxins of Vibrio cholerae and Escherichia coli. Although the mechanisms responsible for the noncytotoxic(More)
The procedures outlined herein apply to seventeen women's ready-to-wear departments, four women's accessories departments and one men's clothing department, all for four Los Angeles stores, and to six ready-to-wear and three accessory departments in the basement section of the Downtown store, a total of thirty-one departments.
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