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We investigated the utility of the Cambridge Behavioural Inventory (CBI), a carer-completed questionnaire, in a large cohort with Parkinson's disease (PD) (n = 215). In a sub-cohort of 112 patients with PD, the CBI was found to be a valid instrument compared with the Neuropsychiatric Inventory, PDQ-39 and UPDRS, with high internal consistency. Furthermore,(More)
In this research, we model a semiconductor wafer fabrication process as a complex job shop, and adapt a Modified Shifting Bottleneck Heuristic (MSBH) to facilitate the multi-criteria optimization of makespan, cycle time, and total weighted tardiness using a desirability function. The desirability function is implemented at two different levels of the MSBH:(More)
This paper describes how a large number of products are scheduled to run in parallel on a pool of wire-bond machines to meet weekly demand. We seek to maximize demand fulfillment subject to system constraints. The schedule is generated by a simulation engine and used to control the machines at execution time and also to plan for the start of material. By(More)
Many companies utilize a number of complex product distribution networks to transport various types of goods. Most of their distribution networks consist of transporting goods from their suppliers to their Distribution Centers (DCs). In the process of transporting goods from suppliers to DCs, cross docking facilities are utilized to consolidate loads in(More)
The semiconductor industry is rapidly expanding worldwide. With the continuing advancement of technology, companies are continually striving to develop and maintain cutting edge products to stay "ahead of the curve." As a result, old and new companies alike often have the need to develop pilot production lines to test new engineering and processing ideas.(More)