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Many areas of science are seeing a data deluge coming from new instruments, myriads of sensors and exponential growth in electronic records. We take two examples – one the analysis of gene sequence data (35339 Alu sequences) and other a study of medical information (over 100,000 patient records) in Indianapolis and their relationship to Geographic and(More)
Discovering the functions of all genes is a central goal of contemporary biomedical research. Despite considerable effort, we are still far from achieving this goal in any metazoan organism. Collectively, the growing body of high-throughput functional genomics data provides evidence of gene function, but remains difficult to interpret. We constructed the(More)
BACKGROUND Human immunodeficiency virus (HIV) research involves ongoing, repetitious sequencing of the HIV genome and the massive accumulation of associated investigational data. As a result, the storage of annotated DNA and/or protein sequences, as well as information retrieval, have become increasingly difficult tasks, with scientists extracting less(More)
Many areas of science are seeing a data deluge coming from new instruments, myriads of sensors and exponential growth in electronic records. We take two examples – one the analysis of gene sequence data (35339 Alu sequences) and other a study of medical information (over 100,000 patient records) in Indianapolis and their relationship to Geographic and(More)
The pressure to reduce the cost of analytic testing makes it tempting to discontinue routine confirmation of urine specimens positive for drugs of abuse by immunoassay. Beyond the economic motivation, the requirement for confirmation should be driven by the positive predictive value of the screening tests. We have quantitated positive predictive values of(More)
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