In hippocampal slice models of epilepsy, two behaviors are seen: short bursts of electrical activity lasting 100 msec and seizure-like electrical activity lasting seconds. The bursts originate from the CA3 region, where there is a high degree of recurrent excitatory connections. Seizures originate from the CA1, where there are fewer recurrent connections.… (More)
Alan Dorval for valuable discussions in the development of this work. The reviewers of this paper made a number of suggestions that improved it dramatically.