Scott A Brown

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Tricyclodecan-9-yl-xanthogenate (D609) has been extensively studied in biological systems and exhibits a variety of biological functions, including antiviral, antitumor, and anti-inflammatory activities. Most of these activities have been largely attributed to the inhibitory effect of D609 on phosphatidylcholine-specific phospholipase C. However, as a(More)
Mirror augmented photovoltaic (MAPV) systems utilize low cost mirrors to couple more light into a photovoltaic (PV) absorber. By increasing the light absorbed, they are expected to produce less expensive electricity. As a substrate candidate for back surface reflector mirrors, two grades of PMMA have been exposed to UV stress from two sources at two(More)
—We report on the design, construction, and initial performance measurements of a low-concentration photovoltaic system based on compound parabolic concentrators (CPCs). The system is approximately a 7× concentration system and uses commercially available laser groove buried contact monocrystalline silicon photovoltaic cells. The CPCs are fabricated using a(More)
Replex Plastics aims to develop a low-cost, low-concentration photovoltaic module using a metallized acrylic reflector designed for use with an inclined single-axis tracker. An asymmetric compound parabolic concentrator is developed and analyzed optimizing the many factors impacting the design, such as tracking strategy, manufacturing process, and cell(More)
Grapefruit juice has been found to cause an increase in the oral bioavailability of many therapeutic agents. Such interactions are believed to result from the mechanism-based inhibition of CYP3A4 activity in the intestine. Furanocoumarin dimers present in the juice have been found to be extremely potent inhibitors of CYP3A4 activity. The aim of this work(More)
In develo p in g p hotovoltaic (PV) technolo gy , it is crucial to p rovide lower cost PV p ower. One of the useful methods is to increase p ower out p ut of conventional modules since the major costs (module manufacturin g , mounts, wirin g , installation labor, etc) tend to scale with s y stem area, and increased p ower out p ut due to im p roved li g ht(More)
The aim of this work was to formulate Alstonia boonei dried stem bark powder into tablets by wet granulation method using acacia, gelatine and sodium carboxymethyl cellulose as binders at concentrations of 1, 2, 4 and 8% w/w. The phytochemistry of the stem bark of Alstonia boonei was evaluated. The micromeritic properties of the granules prepared were(More)
The aminoglycoside (AG) 3'-phosphotransferases [APH(3')s] are an important class of modifying enzymes which confer high-level resistance to those AGs actively modified by the enzymes. They catalyze the transfer of the terminal phosphate from ATP to the drug, thus preventing the AG s action at the 70S ribosome. These enzymes, which utilize ATP as a(More)
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