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  • Scot J Matkovich, Wei Wang, +6 authors Gerald W. Dorn
  • Biology, Medicine
  • Circulation research
  • 2010 (First Publication: 8 January 2010)
  • RATIONALE MicroRNA (miR)-133a regulates cardiac and skeletal muscle differentiation and plays an important role in cardiac development. Because miR-133a levels decrease during reactive cardiacContinue Reading
  • Scot J Matkovich, Derek J. Van Booven, +7 authors Gerald W. Dorn
  • Medicine
  • Circulation
  • 2009 (First Publication: 23 February 2009)
  • BACKGROUND Much has been learned about transcriptional control of cardiac gene expression in clinical and experimental congestive heart failure (CHF), but less is known about dynamic regulation ofContinue Reading
  • Scot J Matkovich, John Richard Edwards, Tiffani C. Grossenheider, Cristina de Guzman Strong, Gerald W. Dorn
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 2014 (First Publication: 28 July 2014)
  • Significance The role of noncoding RNAs in mammalian biology is of great interest, especially since the Encyclopedia of DNA Elements results were published. We and others have studied microRNAs inContinue Reading
  • Nikhil deSouza, Steven R Reiken, Karol Ondrias, Yi-ming Yang, Scot J Matkovich, Andrew R. Marks
  • Biology, Medicine
  • The Journal of Biological Chemistry
  • 2002 (First Publication: 18 October 2002)
  • The inositol 1,4,5-trisphosphate receptor (IP3R) is a ubiquitously expressed intracellular calcium (Ca2+) release channel on the endoplasmic reticulum. IP3Rs play key roles in controlling Ca2+Continue Reading
  • Shali Chen, Prasanth Nair Puthanveetil, Biao Feng, Scot J Matkovich, Gerald W. Dorn II, Subrata Chakrabarti
  • Medicine, Biology
  • Journal of cellular and molecular medicine
  • 2014 (First Publication: 16 January 2014)
  • Diabetic cardiomyopathy is a cascade of complex events leading to eventual failure of the heart and cardiac fibrosis being considered as one of its major causes. miR-133a is one of the mostContinue Reading