Saxena Vikas

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The review of literature showed that cinnoline derivatives were found to elicit many pharmacological actions like anti-hypertensive, antithrombotic, antihistamine, antileukemic, CNS activity, anti-tumor, antibacterial and antisecretory activity. In the substituted Cinnoline thiophene series, the compounds which are halogen mainly Chloro, Bromo and Fluoro(More)
BACKGROUND The Cinnoline moiety and Sulphonamide moiety both have good antimicrobial properties. METHODS In the present study both the moieties were condensed to synthesize substituted cinnoline sulphonamide derivatives using intramolecular cyclization followed by diazotization in order to get synergistic activity. RESULTS These derivatives particularly(More)
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