Saurabh Sharma

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Painful neuropathy, a common complication of diabetes mellitus is characterized by allodynia and hyperalgesia. Recent studies emphasized on the role of non-neuronal cells, particularly microglia in the development of neuronal hypersensitivity. The purpose of the present study is to evaluate the effect of minocyline, a selective inhibitor of microglial(More)
Mexican blind cavefish exhibit an unconditioned wall-following behavior in response to novel environments. Similar behaviors have been observed in a wide variety of animals, but the biological significance and evolutionary history of this behavior are largely unknown. In this study, the behaviors of Mexican blind cavefish (Astyanax sp.) and sighted Mexican(More)
Red mud, an aluminum industry waste, has been converted into an inexpensive and efficient adsorbent. The product obtained has been characterized and utilized in batch and column operations for the removal of cadmium and zinc from aqueous solutions over a wide range of initial metal ion concentrations (1.78 x 10(-5) to 1.78 x 10(-3) M for Cd2+ and 3.06 x(More)
Objective. To determine predictors of patient adherence to CPAP. Design. A retrospective chart review identified patients with AHI values greater than 15 who were recommended to receive CPAP. Compliance was measured at a 1-to 4-month interval and at 1 year. Results. There were 106 of 368 (29%) patients who received CPAP therapy that were compliant with CPAP(More)
PURPOSE Positive surgical margins are an independent predictive factor for biochemical recurrence after radical prostatectomy. We analyzed the incidence of and associative factors for positive surgical margins in a multi-institutional series of 8,418 robotic assisted radical prostatectomies. MATERIALS AND METHODS We analyzed the records of 8,418 patients(More)
A new and novel UV spectrophotometric method has been developed for the determination Cu(II) in synthetic mixture and water samples. The method is based on complex formation of Cu(II) with cefixime immediately in 1,4-dioxan-distilled water medium at room temperature. The complex showed maximum absorption wavelength at 336 nm. Beer’s law is obeyed in the(More)
Background and Aim: Childhood overweight and obesity are becoming a major public health concern all over the world. Change in lifestyles and economic growth have led to sedentary lifestyle and altered dietary patterns. The prevalence and incidence of dental caries in a population is influenced by a number of risk factor such as sex, age, socioeconomic(More)
BACKGROUND AND PURPOSE Efforts to improve postprostatectomy incontinence have led to many modifications in surgical technique. We present our experience with a novel technique to improve continence outcomes in patients who are undergoing robot-assisted radical prostatectomy (RARP). PATIENTS AND METHODS A consecutive series of 159 patients after initiation(More)
AIM We did a population-based cross-sectional study to investigate the prevalence and risk factors of gastroesophageal reflux disease (GERD) in a high altitude area. METHODS An observational study using a validated questionnaire consisting of demographic, lifestyle and dietary characteristics was administered in an interview based format by two clinicians(More)
We report here the direct observation of high resolution structures of assemblies of Alzheimer beta-amyloid oligomers and monomers using liquid atomic force microscopy (AFM). Visualization of nanoscale features of Abeta oligomers (also known as ADDLs) was carried out in tapping mode AFM in F12 solution. Our results indicate that ADDL preparations exist in(More)