Saurabh Saigal

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Placental transfusion has been cornpared in premature and full-term infants. Blood volume measurements showed that the 5-minute transfusion was similar in full-term and premature infants (47% and 50% increase in blood volume from birth) . A larger proportion of the 5-minute transfusion occurred by 1 minute in full-term ( 76%) than in premature infants(More)
Dear Editor, I read the extremely well-written article by Chakrabarti et al. about the incidence of candidemia in critically ill Indian intensive care unit (ICU) patients [1]. The study highlights the high burden of candidemia in Indian ICUs. The patients at admission are at high risk of candidemia despite less severity of illness and, unlike in the West,(More)
Red blood cell volume was estimated indirectly from plasma volume and venous hematocrit measurements in 262 consecutively delivered premature infants of less than 37 weeks' gestation. Infants with respiratory distress syndrome averaged lower red cell volumes (P0.02) than those without. Fatal cases had the lowest volumes. There was a 10.3% mortality from RDS(More)
Dear Editor, Antibiotic resistance is rampant in today’s world; various strategies are being adopted to fight this resistance. These include hand hygiene, contact precautions, isolation of colonized patients and surveillance [1]. Apart from these the Surviving Sepsis Campaign guidelines recommend a strategy based on de-escalation of antibiotics as soon as(More)
Blood volume and clinical data are reported on 8 premature and 3 full-term infants who presented with symptoms apparently due to polycythemia or hypervolemia. These cases termed 'symptomatic neonatal plethora' were caused by large placental transfusions associated with delayed clamping of the umbilical cord. Tachypnea, mild cyanosis, plethoric skin color,(More)
AIM To study the factors associated with outcome in acute liver failure (ALF) in an intensive care unit (ICU). METHODS Consecutive patients with ALF admitted to the ICU from August 2003 to April 2010 were included. Factors associated with the primary outcome, death or survival, were compared. RESULTS Of 52 patients of median age 19 years (range 3-65),(More)
PURPOSE This study was intended to determine whether anaerobic muscle performance is deficient in 5- to 7-yr-old children of extremely low birthweight (ELBW, 500-999 g) and very low birthweight (VLBW, 1000-1499 g). METHODS Fourteen ELBW and 20 VLBW children were compared with 24 normal birthweight (NBW, >2500 g) term controls. Peak (PP) and mean (MP)(More)
Dear Editor, We read the recent article by Debaty et al. [1] with great interest. The methodology used in this trial is of high quality, but the participants were a non-selected study population, of which 80 % were patients with a nonshockable rhythm and, therefore, barely 20 % had a shockable rhythm. This is in contrast to earlier hypothermia trials which(More)
Dear Editor, Severe sepsis and septic shock are progressively severe stages of the host’s systemic inflammatory response to infection and are associated with high mortality. The inflammatory response to infection is complex; repeated failed efforts have been made in the last decade to block the activity of these biochemical triggers such as endotoxin, tumor(More)
This study was intended to determine the effects of extremely low birthweight (ELBW, 500 to 999 g) and very low birthweight (VLBW, 1000 to 1499 g) on neuromotor ability in 5- to 7-year-old children. Fourteen ELBW and 20 VLBW children were compared with 24 term control children of normal birthweight (NBW, >2500 g). Using quantitative assessment instruments,(More)