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The ISWI family of ATP-dependent chromatin remodelers represses transcription by changing nucleosome positions. ISWI regulates nucleosome positioning by requiring a minimal length of extranucleosomal DNA for moving nucleosomes. ISW2 from Saccharomyces cerevisiae, a member of the ISWI family, has a conserved domain called SLIDE (SANT-like ISWI domain) that(More)
This research proposes a pattern/shape-similarity-based clustering approach for time series prediction. This article uses single hidden Markov model (HMM) for clustering and combines it with soft computing techniques (fuzzy inference system/artificial neural network) for the prediction of time series. Instead of using distance function as an index of(More)
This paper presents three novel methods for speaker identification of which two methods utilize both the continuous density hidden Markov model (HMM) and the generalized fuzzy model (GFM), which has the advantages of both Mamdani and Takagi-Sugeno models. In the first method, the HMM is utilized for the extraction of shape-based batch feature vector that is(More)
Nowadays, search and optimization problems have exacting demands of skill accompanied with brevity of time. Genetic Algorithms are endowed with lucrative optimization techniques and are inspired from biological mechanisms such as natural selection, genetic reproduction processes like crossover and mutation. However, the main difficulty encountered in(More)
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