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Relationship between the diversity of the cagA gene of Helicobacter pylori and gastric cancer in Okinawa, Japan
BackgroundHelicobacter pylori CagA protein is considered to be one of the virulence factors associated with gastric cancer. CagA is injected into gastric epithelial cells, undergoes tyrosineExpand
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Association between interleukin-1β-511C/T polymorphism and reflux esophagitis in Japan
BackgroundInterleukin-1β (IL-1β) gene polymorphisms are related to hypochlorhydria and increase the risk of gastric cancer in the presence of Helicobacter pylori infection. However, littleExpand
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Hypoxia-inducible factor-1 alpha and vascular endothelial growth factor expression in ischaemic colitis and ulcerative colitis
Summary Background Hypoxia-inducible factor-1 alpha (HIF-1 alpha) is a transcriptional factor induced by ischaemic crisis in many tissues. Vascular endothelial growth factor (VEGF) is anExpand
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Hypoxia‐inducible factor‐1 alpha and vascular endothelial growth factor expression in ischaemic colitis and ulcerative colitis
Hypoxia‐inducible factor‐1 alpha (HIF‐1 alpha) is a transcriptional factor induced by ischaemic crisis in many tissues. Vascular endothelial growth factor (VEGF) is an important growth factor thatExpand
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Atrophic Gastritis and Salt Intake
Tu1174 Attenuated Progression of Gastric Dysplasia by Administration of Green Tea Catechins in INS-GAS Mice
Backgrounds: Green tea catechins (GTCs) have been shown to provide anti-carcinogenic effects in several laboratory studies. Although the effect of green tea consumption on the risk of gastric cancerExpand
Clinical Relevance and Sequence Analysis of the Helicobacter pylori dupA Region from Two Areas in Japan with Different Gastric Cancer Risks
Aims: We investigated the virulence and sequences of duodenal ulcer-promoting gene A (dupA) of Helicobacter pylori (H. pylori) isolated from 2 areas in Japan with different gastric cancer risks.Expand