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BACKGROUND Penicillamine is a standard therapy for Wilson disease (WD) but some patients have paradoxical worsening. Predictors of such deterioration have not been evaluated. This study documents frequency and predictors of deterioration following treatment in WD. METHODS 59 consecutive patients with neurologic WD and 4 asymptomatic siblings were(More)
PURPOSE To report the frequency and predictors of presenting seizures in cerebral venous sinus thrombosis (CVST) and their influence on seizure recurrence and outcome. METHODS This retrospective study, between 1995 and 2011, included 90 consecutive patients with CVST diagnosed using magnetic resonance imaging (MRI) and magnetic resonance venography (MRV).(More)
OBJECTIVE To evaluate cognitive functions and behavioral changes in the patients with vitamin B12 deficiency neurological syndromes (VBDNS) using detailed clinical psychometric and P3 studies and their response to treatment. METHODS The patients with VBDNS were included and their detailed medical history was recorded. Neurobehavioral and cognitive(More)
OBJECTIVE The frequency and type of neuropathy in vitamin B12 deficiency neurological syndrome (VBDNS) is controversial. This study reports the frequency and type of nerve dysfunction in VBDNS using nerve conduction and sural nerve biopsy and its response to treatment. METHOD Sixty-six patients with VBDNS diagnosed on the basis of low serum vitamin B12(More)
The Support Vector Machine (SVM) is a powerful classification technique that has been used extensively in the field of medical imaging. A model based on SVM with Gaussian RBF kernel is proposed here for the automatic detection of brain tumor from MRI images. Various textural characteristics of the MRI images of human brain are extracted to construct a(More)
The objective of this study is to evaluate clinical picture, radiological findings and response to treatment in patients with antibiotic associated status epilepticus (SE). In a retrospective review, 12 out of 117 (10%) patients with SE had temporal association with antibiotic administration. Their medical history, clinical findings, and duration and type(More)