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OBJECTIVES Abdominal aortic aneurysm (AAA) repair has undergone vast changes in the last decade. We reviewed a national database to evaluate the effect on utilization of services and rupture rates. METHODS From the Centers for Medicare Services (CMS), a 5% inpatient sample was obtained for 1994 to 2003 as beneficiary encrypted files (5% BEF) and as a(More)
PURPOSE The purpose of this study was to delineate the natural history of the progression of asymptomatic carotid stenosis. METHODS In a 10-year period, 1701 carotid arteries in 1004 patients who were asymptomatic were studied with serial duplex scans (mean follow-up period, 28 months; mean number of scans, 2.9/patient). At each visit, stenoses of the(More)
Abdominal aortic aneurysm (AAA) is a vascular condition where the use of a biomechanics-based assessment for patient-specific risk assessment is a promising approach for clinical management of the disease. Among various factors that affect such assessment, AAA wall thickness is expected to be an important factor. However, regionally varying patient-specific(More)
PURPOSE The purpose of this study was to define the clinical features of aortic aneurysms occurring in heart transplant recipients. METHODS Among the 734 patients who have undergone heart transplantation at our institution over the last 14 years, we have identified 12 patients (1.6% incidence) with aortic aneurysms (9 infrarenal, 3 thoracoabdominal),(More)
BACKGROUND To evaluate our experience with staged carotid endarterectomy (CEA) followed by coronary artery bypass grafting (CABG) within the perioperative period for patients with severe carotid and coronary artery disease. METHODS From 1998 to August of 2010, 40 patients who were referred for isolated coronary surgery were found to have significant(More)
OBJECTIVE This study aims to review retrospectively the records of patients treated with carotid artery stenting (CAS) to investigate the potential correlations between clinical variables, distal protection filter (DPF) type and characteristics, and 30-day peri-/postprocedural outcomes. METHODS This is a multicenter, single-arm, nonrandomized(More)
PURPOSE Although aortic aneurysm (AA) is primarily a disease of older age groups, younger (< 51 years) patients infrequently are admitted requiring AA surgery. We sought to compare the characteristics of these patients with those of a randomly selected group of older patients with AA. METHODS We identified 26 patients with AA (group I) under age 51 (mean(More)
OBJECTIVES Endovascular aneurysm repair (EVAR) has changed the practice of abdominal aortic aneurysm (AAA) surgery. We examined a national Medicare database to establish the effect of EVAR introduction into the United States. METHODS A 5% random sample of inpatient Medicare claims from 2000 to 2003 was queried using International Classification of(More)
We recently identified three distinct T helper pathways which contribute to interleukin-2 (IL-2) production by human peripheral blood lymphocytes following stimulation with HLA alloantigens. In two of these pathways, CD4+ T helper cells respond to alloantigen using either self antigen-presenting cells (sAPC)* or allogeneic antigen-presenting cells (aAPC). A(More)
Abdominal aortic aneurysm (AAA) rupture is the clinical manifestation of an induced force exceeding the resistance provided by the strength of the arterial wall. This force is most frequently assumed to be the product of a uniform luminal pressure acting along the diseased wall. However fluid dynamics is a known contributor to the pathogenesis of AAAs, and(More)