Sathish Periyasamy

Mohammad Azhar Aziz4
Zeyad Yousef3
Ahmad Deeb3
Mohammed Afzal Khan2
Ebthehal Al Sheikh2
4Mohammad Azhar Aziz
3Zeyad Yousef
3Ahmad Deeb
2Mohammed Afzal Khan
2Ebthehal Al Sheikh
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Genomic abnormalities leading to colorectal cancer (CRC) include somatic events causing copy number aberrations (CNAs) as well as copy neutral manifestations such as loss of heterozygosity (LOH) and uniparental disomy (UPD). We studied the causal effect of these events by analyzing high resolution cytogenetic microarray data of 15 tumor-normal paired(More)
Colorectal cancer (CRC), which has high prevalence in Saudi Arabia and worldwide, needs better understanding by exploiting the latest available cytogenetic microarrays. We used biopsy tissue from consenting colorectal cancer patients to extract DNA and carry out microarray analysis using a CytoScan HD platform from Affymetrix. Patient specific comparisons(More)
  • Mohammad Azhar Aziz, Sathish Periyasamy, Zeyad Al Yousef, Ibrahim AlAbdulkarim, Majed Al Otaibi, Abdulaziz Alfahed +2 others
  • 2014
Integrated analysis of genomic and transcriptomic level changes holds promise for a better understanding of colorectal cancer (CRC) biology. There is a pertinent need to explain the functional effect of genome level changes by integrating the information at the transcript level. Using high resolution cytogenetics array, we had earlier identified driver(More)
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