Learn More
Previous studies of childhood traumatic brain injury (TBI) have emphasized injury-related variables rather than environmental factors as predictors of recovery. We addressed this concern using data collected during a prospective study of children with either TBI or orthopedic injuries (OI) and their families. Participants included 53 children with severe(More)
Recent emphasis on high resolution gradient echo studies in functional imaging has led to the conclusion that there are likely three domains of response to the blood circulation in the brain when considering field inhomogeneity effects of the venous blood pre- and during activation. The first is a coherent effect due to large or macroscopic vessels on the(More)
This study examined recovery over the first year following traumatic brain injury (TBI) in children 6-12 years of age. Forty-two children with severe TBI and 52 with moderate TBI were compared to 58 children with orthopedic injuries. The children and their families were evaluated at a baseline assessment and at 6- and 12-month follow-ups. Findings(More)
PURPOSE Our goal was to determine whether functional MRI on a standard 1.5 T system can localize activation during a visual vigilance sustained attention task and whether this corresponds to results described in a PET investigation of a similar task. METHOD Sixteen volunteers were studied on a 1.5 T system using a gradient echo technique. A single axial(More)
PURPOSE We evaluated factors that influence MR signal changes during photic stimulation of the visual cortex. We also tested the hypothesis that functional MR imaging response corresponds to electroencephalographic (EEG) synchronization after photic stimulation. METHODS Thirty-eight healthy subjects, 20 men and 18 women, underwent photic stimulation of(More)
Dear Editor, All-trans retinoic acid (ATRA) has become the mainstay in the treatment of acute promyelocytic leukemia (APL) because addition of ATRA to anthracyclines has been shown to improve disease-free survival and overall survival compared to chemotherapy alone [1]. ATRA induces the differentiation of leukemic promyelocytes into mature cells via its(More)
  • 1