Sascha Seifert

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Whole body CT scanning is a common diagnosis technique for discovering early signs of metastasis or for differential diagnosis. Automatic parsing and segmentation of multiple organs and semantic navigation inside the body can help the clinician in efficiently obtaining accurate diagnosis. However, dealing with the large amount of data of a full body scan is(More)
Diagnosis and treatment planning for patients can be significantly improved by comparing with clinical images of other patients with similar anatomical and pathological characteristics. This requires the images to be annotated using common vocabulary from clinical ontologies. Current approaches to such annotation are typically manual, consuming extensive(More)
For preoperative planning and intraoperative support, segmentation of soft tissue structures from the cervical region is a prerequisite. Main activities have been started in the past to segment vertebrae from CT images. But soft tissue structures have been neglected. There is only little research work about segmentation of the spinal chord and the trachea,(More)
Automated segmentation of the esophagus in CT images is of high value to radiologists for oncological examinations of the mediastinum. It can serve as a guideline and prevent confusion with pathological tissue. However, segmentation is a challenging problem due to low contrast and versatile appearance of the esophagus. In this paper, a two step method is(More)
A good application design is crucial for uncomplicated cooperation between software developers with different programming skills, such as researchers and students at university , as in our case. That's why MEDIFRAME features developmental tasks isolated by skill sets. Abstract—In this paper we will give an overview of our cross-platform software framework(More)
In this paper we propose a novel learning–based CBIR method for fast content–based retrieval of similar 3D images based on the intrinsic Random Forest (RF) similarity. Furthermore, we allow the combination of flexible user–defined semantics (in the form of retrieval contexts and high–level concepts) and appearance–based (low–level) features in order to(More)
Examinations of the spinal column with both, Magnetic Resonance (MR) imaging and Computed Tomography (CT), often require a precise three-dimensional positioning, angulation and labeling of the spinal disks and the vertebrae. A fully automatic and robust approach is a prerequisite for an automated scan alignment as well as for the segmentation and analysis(More)
For surgical planning in spine surgery, the segmentation of anatomical structures is a prerequisite. Past efforts focussed on the segmentation of vertebrae from tomographic data, but soft tissue structures have, for the most part, been neglected. Only sparse research work has been done for the spinal cord and the trachea. However, as far as the author is(More)
The current diagnostic process at hospitals is mainly based on reviewing and comparing images coming from multiple time points and modalities in order to monitor disease progression over a period of time. However, for ambiguous cases the radiologist deeply relies on reference literature or second opinion. Although there is a vast amount of acquired images(More)