Sasa S. Zivic

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BACKGROUND Compression therapy is the most widely used treatment for venous leg ulcers and it was used in different forms for more than 400 years. Published healing rates of venous ulcers obtained with compression therapy vary widely from 40-95%. According to numerous studies, it has been suggested that the application of external pressure to the calf(More)
Sirs, During 2009, a pandemic influenza A H1N1 virus emerged end spread all over the world [1]. Renal involvement in influenza A virus infection is rare, but one case of hemolytic uremic syndrome (HUS) during season influenza has been reported [2]. We present a patient with novel A H1N1 virus complicated with HUS. A previously healthy 11-year-old boy was(More)
Venous thromboembolism is a relevant social and health care problem because of its high incidence among patients who undergo surgery (20–30% after general surgical operations and 50–75% after orthopedic procedures), its pulmonary embolism-related mortality rate, and its long-term sequelae (postthrombotic syndrome and ulceration), which may be disabling.(More)
BACKGROUND Venous leg ulcers (VLU) have a huge social and economic impact. An estimated 1.5% of European adults will suffer a venous ulcer at some point in their lives. Despite the widespread use of bandaging with high pressure in the treatment of this condition, recurrence rates range between 25% to 70%. Numerous studies have suggested that the compression(More)
BACKGROUND/AIM Insulin glargine is a long-acting insulin analog that mimics normal basal insulin secretion without pronounced peaks. The aim of this study was to compare insulin glargine with isophane insulin (NPH insulin) for basal insulin supply in patients with type 1 diabetes. METHODS A total of 48 type 1 diabetics on long term conventional intensive(More)
Urinary levels of beta 2 microglobulin (beta 2 MG) and dipeptidipeptidse IV (DPP IV) were measured in 30 insulin dependent diabetes mellitus children aged 5 to 18 years. The control group consisted of 30 healthy children. Metabolic control (HbA1C) and the duration of diabetes were directly correlated with the levels of beta 2 MG and DPP IV. Beta 2 MG(More)
BACKGROUND Venous ulcers are a major health problem because of their high prevalence and associated high cost of care. Compression therapy is the most widely used treatment for this condition. The vast majority of published articles on compression therapy present the results in the treatment of venous ulcers usually up to 15 to 20 cm(2). However, there are(More)
Diabetes mellitus is a metabolic disease characterized by inadequate secretion of insulin. Polyamine oxidase (PAO), a FAD-containing enzyme is involved in the biodegradation of Sp and Spd, catalyzing the oxidative deamination of Sp and Spd, resulting in production of amonia (NH3), corresponding amino aldehydes and H2O2. Malondialdehyde (MDA) and acrolein(More)
AIM The aim of our study was to establish the efficiency of fibrin sealant in the prevention of pocket related complications in patients undergoing pacemaker implantation who are receiving anticoagulant treatment. METHODS The study was performed on 40 and 41 patients prospectively randomized into treatment and control groups who underwent pacemaker(More)
Under physiological conditions insulin controls the metabolism of carbohydrates, lipids and proteins. Diabetes mellitus is a metabolic disease characterized by a disturbance in the intermediary metabolism of glucose and glucose-induced insulin release. Arginase (L-arginine amidinohydrolase, EC modulates nitric oxide synthase activity by regulating(More)