Saritha C. Thumma

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BACKGROUND Aberrant cap-dependent translation is implicated in tumorigenesis in multiple tumor types including mesothelioma. In this study, disabling the eIF4F complex by targeting eIF4E with eIF4E-specific antisense oligonucleotide (4EASO) is assessed as a therapy for mesothelioma. METHODS Mesothelioma cells were transfected with 4EASO, designed to(More)
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