Sarina Kundi

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Patients with spinal cord injury (SCI) are permanently paralysed and anaesthetic below the lesion. This morbidity is attributed to the deposition of a dense scar at the injury site, the cellular components of which secrete axon growth inhibitory ligands that prevent severed axons reconnecting with denervated targets. Another complication of SCI is wound(More)
It is estimated that approximately 2.5 million people are affected by Spinal Cord Injury (SCI), with more than 130,000 new cases reported each year (International Campaign for Cures of Spinal Cord Injury Paralysis). Although there is currently no cure for SCI, various strategies including rehabilitative, cellular and molecular therapies have been tested in(More)
The poor or lack of injured adult central nervous system (CNS) axon regeneration results in devastating consequences and poor functional recovery. The interplay between the intrinsic and extrinsic factors contributes to robust inhibition of axon regeneration of injured CNS neurons. The insufficient or lack of trophic support for injured neurons is(More)
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