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Early (2 weeks) vs. late (8 weeks) initiation of highly active antiretroviral treatment (HAART) significantly enhance survival of severely immunosuppressed HIV-infected adults with newly diagnosed tuberculosis: results of the CAMELIA clinical trial Background Tuberculosis (TB) remains the largest cause of death among people living with HIV/AIDS, especially(More)
OBJECTIVE To investigate the impact of tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) upon immunological recovery and the T-cell compartment after initiation of TB and antiretroviral therapy (ART). DESIGN AND METHODS We prospectively evaluated T-cell immunophenotypes by flow cytometry and cytokines by Luminex assays in a(More)
Background This study aims to evaluate the reconstitution of NK cell functions in HIV/TB co-infected patients developing IRIS versus those not having IRIS after TB and anti-retroviral treatment initiation. Methods (i) 138 HIV+/TB+ patients enrolled in the CAMELIA trial (ANRS 1295-CIPRA/KH001-DAIDS-ES ID10425) in Cambodia and 36 HIV+ patients with CD4 + T(More)
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