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Many studies have shown that primary prostate cancers are multifocal and are composed of multiple genetically distinct cancer cell clones. Whether or not multiclonal primary prostate cancers typically give rise to multiclonal or monoclonal prostate cancer metastases is largely unknown, although studies at single chromosomal loci are consistent with the(More)
We know from animal studies that a stimulating and enriched environment can enhance recovery after stroke, but little is known about the effects of an enriched sound environment on recovery from neural damage in humans. In humans, music listening activates a wide-spread bilateral network of brain regions related to attention, semantic processing, memory,(More)
Our surrounding auditory environment has a dramatic influence on the development of basic auditory and cognitive skills, but little is known about how it influences the recovery of these skills after neural damage. Here, we studied the long-term effects of daily music and speech listening on auditory sensory memory after middle cerebral artery (MCA) stroke.(More)
PURPOSE OF THE STUDY During aging, musical activities can help maintain physical and mental health and cognitive abilities, but their rehabilitative use has not been systematically explored in persons with dementia (PWDs). Our aim was to determine the efficacy of a novel music intervention based on coaching the caregivers of PWDs to use either singing or(More)
Music is a highly complex and versatile stimulus for the brain that engages many temporal, frontal, parietal, cerebellar, and subcortical areas involved in auditory, cognitive, emotional, and motor processing. Regular musical activities have been shown to effectively enhance the structure and function of many brain areas, making music a potential tool also(More)
Email and RSS alerting Sign up for email alerts, and subscribe to this journal's RSS feeds at http://brain.oxfordjournals.org image downloads PowerPoint® Images from this journal can be downloaded with one click as a PowerPoint slide. We know from animal studies that a stimulating and enriched environment can enhance recovery after stroke, but little is(More)
Finland 1 To the Editor: Behavioral and psychological symptoms of dementia (BPSD), such as depression and anxiety are highly prevalent symptoms in persons with dementia (PWDs) and represent one of the most complex, stressful, and costly aspects of dementia care 1. Previous studies have demonstrated that the capacity of music to evoke emotions and memories(More)
Finland 1 To the Editor: Behavioral and psychological symptoms of dementia (BPSD), such as depression and anxiety are highly prevalent symptoms in persons with dementia (PWDs) and represent one of the most complex, stressful, and costly aspects of dementia care 1. Previous studies have demonstrated that the capacity of music to evoke emotions and memories(More)
Recent evidence suggests that music-based interventions can be beneficial in maintaining cognitive, emotional, and social functioning in persons with dementia (PWDs). Our aim was to determine how clinical, demographic, and musical background factors influence the cognitive and emotional efficacy of caregiver-implemented musical activities in PWDs. In a(More)