Sarfraz A Saleemi

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BACKGROUND AND OBJECTIVES Middle Eastern respiratory syndrome caused by novel coronavirus (MERS CoV) has been a major public health challenge since it was first described in 2012 in Saudi Arabia. So far, there is no effective treatment for this serious illness, which features a high mortality rate. We report an initial experience of the use of ribavirin and(More)
Bronchiolitis obliterans (BO) is a serious noninfectious pulmonary complication following allogeneic bone marrow transplantation (BMT). Azithromycin, a macrolide antibiotic, may have a beneficial effect in BO through its anti-inflammatory effect. The aim of the current study was to investigate the potential effect of azithromycin on pulmonary function tests(More)
Portopulmoanry hypertension (POPH) is a form of pulmonary arterial hypertension (PAH) associated with portal hypertension with or without underlying chronic liver disease. POPH is increasingly recognized and recent evidence suggests that it is one of the leading causes of PAH. The pathophysiology of POPH is poorly understood although the pathological(More)
BACKGROUND Extensive research has been devoted to cystic fibrosis-related brochiectasis, compared with non-cystic fibrosis bronchiectasis but the latter is more common and results in significant morbidity and mortality. We assessed the relationship between pulmonary function test (PFT) findings and sputum bacteriology, blood gases, number of hospital(More)
OBJECTIVES Bronchiolitis obliterans syndrome is a significant postallogeneic hematopoietic stem cell transplant problem. Recent data in lung transplant patients suggest an association with gastroesophageal reflux disease and bronchiolitis obliterans syndrome. We studied posthematopoietic stem cell transplant patients with bronchiolitis obliterans syndrome(More)
more of the respiratory findings of cough, dyspnea, hypoxia or findings of pneumonia or acute respiratory distress syndrome (ARDS) on chest x-ray and travel within 10 days to high risk areas such as China, Hong Kong, Singapore and Vietnam or close contact within 10 days with a SARS suspect or a person who has traveled to high risk area within last 10 days.1(More)
Portopulmonary hypertension (POPH) is defined as pulmonary arterial hypertension (PAH) complicated by portal hypertension, with or without advanced hepatic disease. Significant percentage of patients with cirrhotic liver disease has high cardiac output and subsequently elevated pulmonary arterial pressures (PAP). However, patients with POPH develop a(More)
Endobronchial tuberculosis TB can be present in various forms including ulceration, hyperemia and granulation tissue and rarely as mass lesion. We present a case of TB presenting as endobronchial tumor mimicking lung cancer on bronchoscopic examination. The histology of the tumor showed caseating granuloma and bronchial lavage culture was positive for(More)