Sarah Trunk

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Krankenhäuser stehen unter einem ständig wachsenden Kostendruck. Der OP-Bereich ist der kostenintensivste Arbeitsplatz in einem Krankenhaus und er stellt einen bedeutenden Flaschenhals bei der Versorgung chirurgischer Patienten dar. Durch eine verbesserte Koordination der Arbeitsabläufe eröffnen sich erhebliche Einspareffekte, die unter einem DRG-System(More)
Economic aspects have gained increasing importance in recent years. The operating room (OR) is the most cost-intensive sector and determines the turnover process of a surgical patient within the hospital. Thus, optimisation of workflow processes is of particular interest for health care providers. If the results of surgery are viewed as a product,(More)
Oxidative cleavage of alkenes is a widely employed process allowing oxyfunctionalization to corresponding carbonyl compounds. Recently, a novel biocatalytic oxidative alkene cleavage activity on styrene derivatives was identified in TM1459 from Thermotoga maritima. In this work we engineered the enzyme by site-saturation mutagenesis of active site amino(More)
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