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Throughout the United States and Europe, demand for airport use has been increasing rapidly, while airport capacity has been stagnating. Over the last ten years the number of passengers has increased by more than 50 percent and is expected to continue increasing at this rate. Acute congestion in many major airports has been the unfortunate result. For U.S.(More)
We address the problem of determining how to reroute aircraft in the air traffic control system when faced with dynamically changing weather conditions. The overall objective of this problem is the minimization of delay costs. This problem is of primary concern in the European air traffic control system and in particular regions within the US air traffic(More)
OBJECTIVE The level of T cell activation in untreated HIV disease is strongly and independently associated with risk of immunologic and clinical progression. The factors that influence the level of activation, however, are not fully defined. Since endogenous glucocorticoids are important in regulating inflammation, we sought to determine whether less(More)
In this paper, a pseudopolynomial time algorithm is presented for solving the integral time-dependent quickest flow problem (TDQFP) and its multiple source and sink counterparts: the time-dependent evacuation and quickest transshipment problems. A more widely known, though less general version, is the quickest flow problem (QFP). The QFP has historically(More)
Patients with end-stage kidney disease on peritoneal dialysis often develop progressive scarring of the peritoneal tissues. This manifests as submesothelial thickening and is associated with increased vascularization that leads to ultrafiltration dysfunction. Hypoxia induces a characteristic series of responses including angiogenesis and fibrosis. We(More)
Page numbers When referring to this paper, please check the page numbers in the published version and cite these. General rights Copyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the(More)
Sublingual hematoma secondary to short-acting anticoagulants such as warfarin has been labeled "pseudo-Ludwig's angina" to distinguish it from the classic syndrome of localized infection and swelling involving the upper airway. Sublingual hematoma with airway compromise secondary to brodifacoum, a common long-acting anticoagulant rodenticide, has only been(More)
Forty children aged 3-6 years responded to items representing nine wh-question forms. Questions referred to three types of referential sources (conditions) based on immediacy and visual availability. The hierarchies of wh-question forms based on degree of difficulty were similar to those described in previous investigations. However, a significant(More)
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