Sarah Rogers

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Postmenopausal women with established vertebral osteoporosis were studied for 2 years to determine the terminal elimination half-life and the duration of response to treatment with intravenous alendronate (30 mg) given over 4 days. The urinary excretion of alendronate followed a multiexponential decline. Approximately 50% of the total dose was excreted over(More)
RATIONALE AND OBJECTIVES To investigate the utility of a computer-aided diagnosis (CAD) in the task of differentiating malignant nodules from benign nodules based on quantitative features extracted from volumetric thin section CT image data acquired before and after the injection of contrast media. MATERIALS AND METHODS 35 volumetric CT datasets of(More)
In the current study, the effects of reconstruction algorithms on quantitative measures derived from computed tomographic (CT) lung images were assessed in patients with emphysema. CT image data sets were reconstructed with a standard algorithm and alternative algorithm(s) for 42 subjects. Algorithms were grouped as overenhancing, sharp, standard, or(More)
RATIONALE AND OBJECTIVES The objective is to study the incremental effects of using a computer-aided lung nodule detection (CAD) system on the performance of a large pool of observers. MATERIALS AND METHODS A set of eight thin-section computed tomographic data sets with limited longitudinal coverage, containing a total of 22 lung nodules, was analyzed by(More)
RATIONALE AND OBJECTIVES To study the agreement in treatment response classifications between unidimensional (1D), bidimensional (2D), and volumetric (3D) methods of measuring metastatic lung nodules on chest computed tomography (CT). MATERIALS AND METHODS Chest CT scans of 15 patients undergoing treatment for metastatic colorectal, renal cell, or breast(More)
RATIONALE AND OBJECTIVES We sought to investigate the utility of a computer-aided diagnosis in the task of differentiating malignant nodules from benign nodules based on single thin-section computed tomography image data. MATERIALS AND METHODS Eighty-one thin-section computed tomography data sets of solitary pulmonary nodules with proven diagnoses (48(More)
BACKGROUND Calcipotriene and betamethasone dipropionate are topical treatments for psoriasis vulgaris. Their mode of action is different. Improved risk/benefit may result with concomitant use of the two compounds together. A new vehicle has been created with the objective of obtaining optimal stability of both calcipotriene and betamethasone dipropionate in(More)
Three general growth models (Logistics, Gompertz and Saturation Kinetics) were compared for describing growth of broilers. Accuracy of fit, case of use and interpretation of data were used to compare the models. Data from a broiler feed restriction study was used to illustrate the parameter differences between the models. All three models accurately(More)
Two experiments were conducted to determine the relationship of supplemental Trp on liver fat accumulation and egg production during aflatoxicosis in laying hens. In Experiment 1, two levels of Trp (0 and 2,000 ppm; basal = .16% Trp) and two levels of aflatoxin (AFLA) (0 and 10 ppm) were supplemented to a complete layer ration. In Experiment 2, a third(More)
The relationship between starvation heat production (SHP) in kJ/d and body weight (W) in kg for domestic fowl was examined with compiled calorimetric data for 294 fowls (Johnson and Farrell, 1985). Linear regression analyses using ordinary least squares methods were performed before and after transformation of the data to a logarithmic scale (base = 10).(More)