Sarah Rasheed

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CONTEXT AND OBJECTIVE Obesity is associated with activation of the TNF-α system, increased inflammatory markers, and insulin resistance. Although studies in rodents suggest that attenuation of TNF activity improves glucose homeostasis, the effect of prolonged inhibition of TNF-α with etanercept on inflammation and glucose homeostasis in a human model of(More)
Loss-of-function of the potassium-chloride cotransporter 3 (KCC3) causes hereditary motor and sensory neuropathy with agenesis of the corpus callosum (HMSN/ACC), a severe neurodegenerative disease associated with defective midline crossing of commissural axons in the brain. Conversely, KCC3 over-expression in breast, ovarian and cervical cancer is(More)
Disruption of the potassium/chloride cotransporter 3 (KCC3), encoded by the SLC12A6 gene, causes hereditary motor and sensory neuropathy associated with agenesis of the corpus callosum (HMSN/ACC), a neurodevelopmental and neurodegenerative disorder affecting both the peripheral nervous system and CNS. However, the precise role of KCC3 in the maintenance of(More)
Missense and protein-truncating mutations of the human potassium-chloride co-transporter 3 gene (KCC3) cause hereditary motor and sensory neuropathy with agenesis of the corpus callosum (HMSN/ACC), which is a severe neurodegenerative disease characterized by axonal dysfunction and neurodevelopmental defects. We previously reported that KCC3-truncating(More)
AIMS To define the patterns of Internet use among physicians who treat inflammatory bowel disease (IBD) and physicians' perceptions of their patients' Internet use. METHODS An online survey about physician and patient use of the Internet was created and e-mailed to gastroenterologists nationwide. Surveys were distributed and collected via an online(More)
Masoud Shekarabi,1 Randal X. Moldrich,5,6 Sarah Rasheed,1 Adéle Salin-Cantegrel,1 Janet Laganière,1 Daniel Rochefort,1 Pascale Hince,1 Karine Huot,1 Rébecca Gaudet,1 Nyoman Kurniawan,6 Susana G. Sotocinal,8 Jennifer Ritchie,8 Patrick A. Dion,1,2 Jeffrey S. Mogil,8 Linda J. Richards,5,7 and Guy A. Rouleau1,3,4 1Center of Excellence in Neuroscience of the(More)
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