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  • David Sanchez Olmos, Douglas Barker, +14 authors Sarah P Blagden
  • Medicine
  • Clinical cancer research : an official journal of…
  • 2011 (First Published: 15 May 2011)
  • PURPOSE GSK461364 is an ATP-competitive inhibitor of polo-like kinase 1 (Plk1). A phase I study of two schedules of intravenous GSK461364 was conducted. EXPERIMENTAL DESIGN GSK461364 wasContinue Reading
  • J-C. Soria, Hui K Gan, +20 authors MichaelJ. Millward
  • Medicine
  • Annals of oncology : official journal of the…
  • 2016 (First Published: 1 December 2016)
  • BACKGROUND Focal adhesion kinase (FAK) is important in cancer growth, survival, invasion, and migration. The purpose of this study was to determine the maximum tolerated dose (MTD), safety,Continue Reading