Sarah Justvig

Publications3
h-index1
Citations46
Highly Influential Citations1
Claim Author Page
Author pages are created from data sourced from our academic publisher partnerships and public sources.

Recommended Authors

  • J. Toretsky
  • 186 Publications • 7,888 Citations
  • A. Üren
  • 138 Publications • 3,395 Citations
  • Hayriye V Erkizan
  • 34 Publications • 1,053 Citations
  • Julie S. Barber-Rotenberg
  • 18 Publications • 769 Citations
  • Publications
  • Influence
A Small Molecule Inhibitor of ETV1, YK-4-279, Prevents Prostate Cancer Growth and Metastasis in a Mouse Xenograft Model
TLDR
YK-4-279 is a potent inhibitor of ETV1 and inhibits both the primary tumor growth and metastasis of fusion positive prostate cancer xenografts and may be evaluated as a potential therapeutic tool for treatment of human prostate cancer at different stages.
Abstract 5453: YK-4-279 inhibits ETS-positive prostate cancer cell metastasis in a mouse xenograft model.
TLDR
It is demonstrated that YK-4-279 decreases tumor growth and inhibits metastasis in fusion-positive prostate cancer cell xenografts and may have an impact on preventing metastases in prostate cancer patients, which is a leading cause of death.
Abstract 2949: YK-4-279 is a small molecule inhibitor of ETV1 and inhibits metastasis in a mouse model
TLDR
It is demonstrated that YK-4-279 is a potent inhibitor of ETV1 and should be further evaluated for its clinical applications in prostate cancer.