Sarah H W Sell

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The total multicenter data from trials with inactivated monovalent influenza A/New Jersey/76 virus vaccine in 2,326 normal children were collected and summarized at Vanderbilt University (Nashville, Tenn.). These combined data provided the best measure of the relative antigenicity and reactogenicity of each manufacturer's vaccine. Children younger than 10(More)
Respiratory syncytial virus ts-1 is a live attenuated experimental vaccine which was administered intranasally to 25 infants 11 to 19 months of age. Clinical evaluation was carried out following a controlled, double-blind protocol which eliminated observer bias, assessed intercurrent illness, and was designed to detect virus transmission. At the low dose of(More)
Normal infants, selected at six months of age for participation in one of two separate studies of polyvalent pneumococcal vaccines, octavalent vaccine for Eli Lilly Laboratories (Indianapolis, Ind.) and 14-valent vaccine from Merck Sharp & Dohme (West Point, Pa.), were assigned randomly to groups to receive vaccine at six and/or 12 months of age or to(More)
There is a growing suspicion that survivors of bacterial meningitis have deficits which may not become apparent until the children encounter the stress of school. Controlled studies are needed to evaluate such subtle sequelae.The first study concerns the intelligence test results of 31 influenzal meningitis survivors, each of whom was paired with a near age(More)
Influenza A/Hong Kong/68-ts-1 [E] (H3N2) vaccine was administered intranasally to 18 seronegative children 14 to 32 months of age. Fourteen children, 78%, shed influenza A/Hong Kong virus for a mean of eight days following vaccination. Sixteen children, 89%, experienced a fourfold or greater rise in hemagglutination-inhibition antibody. Some children(More)
A monovalent, zonally purified, inactivated influenza B vaccine was administered to 29 children, 3 to 6 years of age, and 16 infants, 12 to 28 months of age, as a single dose of 0.25 ml containing 250 chick cell agglutinating units. The vaccine was both antigenic and well tolerated in the older group of preschool children. In the infants the vaccine was(More)
Whether recurrent otitis media in infants and young children is followed by delayed language development was addressed by following 210 normal subjects longitudinally through the first 2 years of life with pneumatic otoscopy and tympanometry performed at every physician encounter. Otitis accounted for 26% of the medical visits. One hundred fifty-six of(More)