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A fundamental assumption in invasion biology is that most invasive species exhibit enhanced performance in their introduced range relative to their home ranges. This idea has given rise to numerous hypotheses explaining "invasion success" by virtue of altered ecological and evolutionary pressures. There are surprisingly few data, however, testing the(More)
The coupled climate models used in the Fourth Assessment Report of the Intergovernmental Panel on Climate Change are evaluated. The evaluation is focused on 12 regions of Australia for the daily simulation of precipitation, minimum temperature, and maximum temperature. The evaluation is based on probability density functions and a simple quantitative(More)
The gut microbiota is vital to host health and, as such, it is important to elucidate the mechanisms altering its composition and diversity. Intestinal helminths are host immunomodulators and have evolved both temporally and spatially in close association with the gut microbiota, resulting in potential mechanistic interplay. Host-helminth and(More)
Toxoplasma gondii is found on all continents and can infect all endothermic vertebrates. Toxoplasmosis is a globally important zoonosis with potentially devastating health impacts both for humans and a range of domestic and wild species. The World Health Organisation have repeatedly recommended the collection of accurate epidemiological data for T. gondii,(More)
An important epidemiological consequence of aggregated host-parasite associations occurs when parasites are vectors of pathogens. Those hosts that attract many vectors will tend to be the focus of transmission. But to what extent, and can we identify characteristics of these key hosts? We investigated these questions with respect to the host-tick(More)
W hy are cows sacred? Travel anywhere in India and they have the right of way. Travel anywhere in the eastern United States and you'll see squirrels, more than likely, as roadkill. Yet both species serve a similar epidemiological function: they receive bites from infected vectors that might otherwise have bitten humans, and they break the chain of pathogen(More)
1. Social network analyses tend to focus on human interactions. However, there is a burgeoning interest in applying graph theory to ecological data from animal populations. Here we show how radio-tracking and capture-mark-recapture data collated from wild rodent populations can be used to generate contact networks. 2. Both radio-tracking and(More)
Deer support high tick intensities, perpetuating tick populations, but they do not support tick-borne pathogen transmission, so are dilution hosts. We test the hypothesis that absence of deer (loss of a dilution host) will result in either an increase or a reduction in tick density, and that the outcome is scale dependent. We use a complementary(More)
communities and alter biodiversity worldwide when they spread extensively in novel habitats. Biological invasions are an increasing problem in this changing world, and ecologists are now considering the factors – environmental, man-made and biological – that influence their outcome. Recent research shows that parasites are a key factor influencing the(More)
PURPOSE Ovarian cancer has a high recurrence and mortality rate. A barrier to improved outcomes includes a lack of accurate models for preclinical testing of novel therapeutics. EXPERIMENTAL DESIGN Clinically relevant, patient-derived tumorgraft models were generated from sequential patients and the first 168 engrafted models are described. Fresh ovarian,(More)