Sarah E Koss

Learn More
Brain size is precisely regulated during development and involves coordination of neural progenitor cell proliferation, differentiation, and survival. The adapter protein ShcA transmits signals from receptor tyrosine kinases via MAPK (mitogen-activated protein kinase)/ERK (extracellular signal-regulated kinase) and PI3K (phosphatidylinositol 3-kinase)/Akt(More)
It has been suggested that, to ensure tooth strength, a minimum of 1 mm of root wall thickness should be left after post preparations. The purpose of this study was to determine the instrument diameter that will not affect this measurement in maxillary first premolars. Post preparations were made in 106 teeth with one and two root canals at a working depth(More)
Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disease in which environmental exposures like virus infection and UV-irradiation trigger activation of the innate and adaptive immune system in genetically predisposed individuals. Heterozygous mutations of the 3' repair exonuclease 1 (TREX1) are associated with SLE. Biallelic mutations in(More)
  • 1