Learn More
Ocean acidification may have severe consequences for marine ecosystems; however, assessing its future impact is difficult because laboratory experiments and field observations are limited by their reduced ecologic complexity and sample period, respectively. In contrast, the geological record contains long-term evidence for a variety of global environmental(More)
UNLABELLED Chaperone-usher pathway (CUP) pili are extracellular organelles produced by Gram-negative bacteria that mediate bacterial pathogenesis. Small-molecule inhibitors of CUP pili, termed pilicides, were rationally designed and shown to inhibit type 1 or P piliation. Here, we show that pilicide ec240 decreased the levels of type 1, P, and S piliation.(More)
UNLABELLED Uropathogenic Escherichia coli (UPEC) is the primary cause of community-acquired urinary tract infections (UTIs). UPEC bind the bladder using type 1 pili, encoded by the fim operon in nearly all E. coli. Assembled type 1 pili terminate in the FimH adhesin, which specifically binds to mannosylated glycoproteins on the bladder epithelium.(More)
The Refuge Manager supervises management activities at the refuge and coordinates scientific work on the Research Natural Area. For brief observational visits, permission may be obtained from the Refuge Manager. The Research Natural Area described in this supplement is part of a Federal system of such tracts established for research and educational(More)
Located at the interface between estuaries and surrounding uplands, tidal marshes are in position to receive and transform material from both adjacent systems. Of particular importance in eutrophic estuarine systems, tidal marshes permanently remove nutrients via two mechanisms-denitrification and long-term burial. Denitrification was measured (monthly) in(More)
  • 1