Sarah Diehl

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We present a Galaxy based web server for processing and visualizing deeply sequenced data. The web server's core functionality consists of a suite of newly developed tools, called deepTools, that enable users with little bioinformatic background to explore the results of their sequencing experiments in a standardized setting. Users can upload pre-processed(More)
MOF (MYST1, KAT8) is the major H4K16 lysine acetyltransferase (KAT) in Drosophila and mammals and is essential for embryonic development. However, little is known regarding the role of MOF in specific cell lineages. Here we analyze the differential role of MOF in proliferating and terminally differentiated tissues at steady state and under stress(More)
Chromatin immunoprecipitation followed by next generation sequencing (ChIP-seq) is a key technique in chromatin research. Although heavily applied, existing ChIP-seq protocols are often highly fine-tuned workflows, optimized for specific experimental requirements. Especially the initial steps of ChIP-seq, particularly chromatin shearing, are deemed to be(More)
  • Jonathan B Tucker, James Martin Center, Nonproliferation Studies, Sarah Diehl, Catherine Auer
  • 2008
Th e James Martin Center for Nonproliferation Studies (CNS) strives to combat the spread of weapons of mass destruction by training the next generation of nonproliferation specialists and disseminating timely information and analysis. A research center at the Monterey Institute of International Studies (an affi liate of Middlebury College), CNS is the(More)
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