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The Influence of Host and Bacterial Genotype on the Development of Disseminated Disease with Mycobacterium tuberculosis
The factors that govern the development of tuberculosis disease are incompletely understood. We hypothesized that some strains of Mycobacterium tuberculosis (M. tuberculosis) are more capable ofExpand
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Genome-wide and fine-resolution association analysis of malaria in West Africa
We report a genome-wide association (GWA) study of severe malaria in The Gambia. The initial GWA scan included 2,500 children genotyped on the Affymetrix 500K GeneChip, and a replication studyExpand
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TM4SF20 ancestral deletion and susceptibility to a pediatric disorder of early language delay and cerebral white matter hyperintensities.
White matter hyperintensities (WMHs) of the brain are important markers of aging and small-vessel disease. WMHs are rare in healthy children and, when observed, often occur with comorbidExpand
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Cytokine release by lipopolysaccharide-stimulated whole blood from patients with typhoid fever.
The ex vivo cytokine response to lipopolysaccharide (LPS) of whole blood from patients with typhoid fever was investigated. Tumor necrosis factor (TNF)-alpha release by LPS-stimulated blood was foundExpand
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Second-Line HIV Therapy Outcomes and Determinants of Mortality at the Largest HIV Referral Center in Southern Vietnam
AbstractThe growing numbers of HIV-infected patients requiring second-line antiretroviral therapy (ART) in Vietnam make essential the evaluation of treatment efficacy to guide treatment strategies.WeExpand
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Geographical distribution and disease associations of the CD45 exon 6 138G variant
CD45 is crucial for normal lymphocyte signalling, and altered CD45 expression has major effects on immune function. Both mice and humans lacking CD45 expression are severely immunodeficient, andExpand
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Bacterial risk factors for treatment failure and relapse among patients with isoniazid resistant tuberculosis
BackgroundDrug resistant tuberculosis (TB) is increasing in prevalence worldwide. Treatment failure and relapse is known to be high for patients with isoniazid resistant TB treated with standardExpand
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“Une Nègre de drame”: Jane Vialle and the Politics of Representation in Colonial Reform, 1945–1953
The French-Congolese Senator, Jane Vialle, was appointed as a French delegate to the United Nations in 1949. During her term she served on the Ad-Hoc Anti-Slavery committee as an expert on AfricanExpand
Immunopathology of Beh 9 et ' s disease
Behqet's disease (BD) is best considered as a systemic vasculitis in which recurrent orogenital ulceration is a prominent feature. In 1937 Hulusi Behqet described the syndrome that bears his name'Expand