Sarah Brown

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Information and Communication Technologies are increasingly intertwined across the economies and societies of developed countries. Protecting these technologies from cyber-threats requires collaborative relationships for exchanging cyber defense data and an ability to establish trusted relationships. The fact that Communication and Information Systems (CIS)(More)
The need for more fluent information sharing has been recognized for years as a major requirement by the cyber security community. Information sharing at present is mostly a slow, inefficient, and manual process that in many cases uses non-structured data sources. It is true that several cyber security data sharing tools have emerged and are currently(More)
Breast cancer stem cells (BCSCs) are pan-resistant to different anticancer agents and responsible for cancer relapse. Disulfiram (DS), an antialcoholism drug, targets CSCs and reverses pan-chemoresistance. The anticancer application of DS is limited by its very short half-life in the bloodstream. This prompted us to develop a liposome-encapsulated DS(More)
Inspiratory muscle training (IMT) has been shown to improve time trial performance in competitive athletes across a range of sports. Surprisingly, however, the effect of specific IMT on surface swimming performance remains un-investigated. Similarly, it is not known whether any ergogenic influence of IMT upon swimming performance is confined to specific(More)
PRESSURE 2 is a multicentre, randomised, double triangular group sequential, parallel group trial involving 2954 patients, comparing High Specification Foam (HSF) and Alternating Pressure Mattresses (APMs) in high risk acute patients for the prevention of new pressure ulcers (PUs). The primary endpoint is time to developing a new Category ≥2 PU from(More)
12/15-Lipoxygenases (LOXs) in monocytes and macrophages generate novel phospholipid-esterified eicosanoids. Here, we report the generation of two additional families of related lipids comprising 15-ketoeicosatetraenoic acid (KETE) attached to four phosphatidylethanolamines (PEs). The lipids are generated basally by 15-LOX in IL-4-stimulated monocytes, are(More)
Liposome-based chemotherapeutics used in the treatment of breast cancer can in principle enhance the therapeutic index of otherwise unencapsulated anticancer drugs. This is partially attributed to the fact that encapsulation of cytotoxic agents within liposomes allows for increased concentrations of the drug to be delivered to the tumor site. In addition,(More)
Across the world, organizations have teams gathering threat data to protect themselves from incoming cyber attacks and maintain a strong cyber security posture. Teams are also sharing information, because along with the data collected internally, organizations need external information to have a comprehensive view of the threat landscape. The information(More)
This paper presents a study that explores the use of mediation in virtual environments (VEs) used for cultural storytelling. A VE was created in which a traditional San story was told. Two forms of mediation were used: visual and audio. Four versions of the VE were implemented, differentiated by the types of mediation included. An experiment was conducted,(More)
Probability and statistics play a vital role in every field of human activity. In particular, they are quantitative tools widely used in the areas of economics and finance. Knowledge of modern probability and statistics is essential for the development of economic and finance theories and for the testing of their validity through robust analysis of(More)