Sarah A. Signor

Publications27
h-index7
Citations294
Highly Influential Citations19
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The Evolution of Gene Expression in cis and trans.
A Large Panel of Drosophila simulans Reveals an Abundance of Common Variants
TLDR
A new panel of 170 inbred genotypes of a North American population of D. simulans is sequence, a valuable complement to the DGRP and other D. melanogaster panels, to attempt to parse the contribution of demography and selection to the patterns observed in this population.
Social effects for locomotion vary between environments in Drosophila melanogaster females
TLDR
It is concluded that IGEs are an important component of social and sexual interactions and that they vary between individuals and abiotic environments in complex ways, with the potential to promote the maintenance of phenotypic variation.
Population genomics of Wolbachia and mtDNA in Drosophila simulans from California
TLDR
A phylogeny of Wolbachia and of mtDNA suggest a recent origin of the infection derived from a single origin, and the first association analysis using this phenotype with the nuclear genome is performed, finding several implicated regions, including one which contains four CAAX-box protein processing genes.
Genetic Convergence in the Evolution of Male-Specific Color Patterns in Drosophila
Evolution of Plasticity in Response to Ethanol between Sister Species with Different Ecological Histories (Drosophila melanogaster and D. simulans)
TLDR
Comparing two species of Drosophila that differ in their adaptation to ethanol is compared, and it is found that D. simulans exhibits cryptic genetic variation in the response to ethanol, while D. melanogaster has almost no genotype-specific variation in reaction norm.
Genetic Basis of a Violation of Dollo’s Law: Re-Evolution of Rotating Sex Combs in Drosophila bipectinata
TLDR
The genetic architecture of the Drosophila sex comb suggests that rotating sex combs may have re-evolved through changes in relatively few genes, and potential developmental mechanisms that may allow lost complex structures to be regained are discussed.
Dynamic changes in gene expression and alternative splicing mediate the response to acute alcohol exposure in Drosophila melanogaster
TLDR
It is found that while D. melanogaster responds to ethanol, there is very little genetic variation in how it responds toanol, suggesting that incorporating time into studies on the response to the environment is important.
Novel approach to quantitative spatial gene expression uncovers genetic stochasticity in the developing Drosophila eye
TLDR
There is considerable variation in the spatial expression pattern of these genes in the eye between species, genotypes, and sexes, and there has been evolution of the regulatory relationship between these genes, and their spatial interrelationships have evolved between species.
Genomic resources for multiple species in the Drosophila ananassae species group
TLDR
The ananassae subgroup is an excellent model system for examining the molecular basis of speciation and phenotypic evolution and new genomic resources will facilitate the genetic analysis of inter- and intraspecific differences in this lineage.
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