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Management of HIV positive pregnancies in Ontario: current status.

• Sarabjit S. Gahir, Gregory J. Anger, Michael Ibrahim, Stanley Read, Micheline Piquette-Miller
• The Canadian journal of clinical pharmacology…
• 2009

BACKGROUND AIDS is one of the biggest health crises we face today. With nearly 20 million women infected with the virus that causes it, HIV, maternal transmission of HIV is increasingly becoming a… (More)

Gestational and pregnane X receptor-mediated regulation of placental ATP-binding cassette drug transporters in mice.

• Sarabjit S. Gahir, Micheline Piquette-Miller
• Drug metabolism and disposition: the biological…
• 2011

The ATP-binding cassette (ABC) drug transporters in the placenta are involved in controlling the exchange of endogenous and exogenous moieties. Pregnane X receptor (PXR) is a nuclear receptor that… (More)

The Role of PXR Genotype and Transporter Expression in the Placental Transport of Lopinavir in Mice

• Sarabjit S. Gahir, Micheline Piquette-Miller
• Pharmaceutics
• 2017

Lopinavir (LPV), an antiretroviral protease inhibitor frequently prescribed in HIV-positive pregnancies, is a substrate of Abcb1 and Abcc2. As differences in placental expression of these… (More)

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