Sara Signorelli

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BACKGROUND Mutations within the DNA binding domain (DBD) of the tumor suppressor p53 are found in >50% of human cancers and may significantly modify p53 secondary structure impairing its function.(More)
Tumor suppressor p53 belongs to the class of intrinsically disordered proteins characterized by large unstructured regions. These proteins can adopt an ensemble of diverse, dynamically interchanging,(More)
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