Sara Lagerholm

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Gastrointestinal carcinoid cells secrete multiple neuroendocrine markers and hormones including 5-HT and chromogranin A. The intracellular signaling pathways that regulate production of bioactive molecules are not completely understood. Our aim was to determine whether activation of the raf-1/MEK/MAPK signal transduction pathway in carcinoid cells could(More)
In this study we have characterized the nucleotide sequence of the cDNA for the growth hormone receptor (GHR) and examined the effects of morphine on the gene transcripts for GHR as well as GH binding protein (GHBP) in the male rat hippocampus and spinal cord. Using reverse transcription-polymerase chain reaction followed by cloning and sequencing, we found(More)
" I don't want to achieve immortality through my work. I want to achieve it through not dying " Woody Allen (1935-?) Papers included in the thesis This thesis is based on the following papers, which are referred to in the text by their Roman numerals: Blomqvist. Distribution of growth hormone receptor mRNA in the brain stem and spinal cord of the rat.(More)
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