Sara J. Whitehead

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BACKGROUND Maternal mortality in Afghanistan is uniformly identified as an issue of primary public-health importance. To guide the implementation of reproductive-health services, we examined the numbers, causes, and preventable factors for maternal deaths among women in four districts. METHODS We did a retrospective cohort study of women of reproductive(More)
OBJECTIVE To describe trends in pregnancy-related mortality and risk factors for pregnancy-related deaths in the United States for the years 1991 through 1997. METHODS In collaboration with the American College of Obstetricians and Gynecologists and state health departments, the Pregnancy Mortality Surveillance System, part of the Division of Reproductive(More)
OBJECTIVE To assess risk factors for legal induced abortion-related deaths. METHODS This is a descriptive epidemiologic study of women dying of complications of induced abortions. Numerator data are from the Abortion Mortality Surveillance System. Denominator data are from the Abortion Surveillance System, which monitors the number and characteristics of(More)
BACKGROUND Herpes simplex virus type 2 infection is important in the HIV epidemic and may contribute to increased HIV transmission. We evaluated the effect of suppressive acyclovir therapy on cervicovaginal HIV-1 shedding. METHODS HIV-1- and herpes simplex virus type 2-coinfected women aged 18-49 years with CD4 counts >200 cells/microL were enrolled in a(More)
BACKGROUND Few studies of microbicide acceptability among HIV-infected women have been done. We assessed Carraguard® vaginal gel acceptability among participants in a randomized, controlled, crossover safety trial in HIV-infected women in Thailand. METHODOLOGY/PRINCIPAL FINDINGS Participants used each of 3 treatments (Carraguard gel, methylcellulose(More)
INTRODUCTION Health utilities of tuberculosis (TB) patients may be diminished by side effects from medication, prolonged treatment duration, physical effects of the disease itself, and social stigma attached to the disease. METHODS We collected health utility data from Thai patients who were on TB treatment or had been successfully treated for TB for the(More)
OBJECTIVES To evaluate the association between maternal herpes simplex virus type 2 seropositivity and genital herpes simplex virus type 2 shedding with perinatal HIV transmission. STUDY DESIGN Evaluation of women who participated in a 1996-1997 perinatal HIV transmission prevention trial in Thailand. METHODS In this nonbreastfeeding population, women(More)
OBJECTIVES To evaluate the acceptability of candidate microbicide Carraguard among couples participating in a safety trial. STUDY DESIGN A 6-month randomized, placebo-controlled trial was conducted in sexually active, low-risk couples in Thailand. METHODS Couples who were monogamous, HIV uninfected, and not regular condom users were enrolled.(More)
The aim of this study is to estimate HIV prevalence and assess sexual behaviors in a high-risk and difficult-to-reach population of clients of female sex workers (FSWs). A modified variation of respondent-driven sampling was conducted among FSWs in Bangkok, where FSWs recruited 3 FSW peers, 1 client, and 1 nonpaying partner. After informed consent was(More)
OBJECTIVES As part of a community-based reproductive health project in rural Tanzania, a maternal and perinatal health care surveillance system was established to monitor pregnancy outcomes. This report presents preliminary results. METHODS Village health workers were trained to collect data during health education visits to pregnant and postpartum women.(More)