Sara Carvalhal

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Centrosomes and cilia are critical eukaryotic organelles which have been in the spotlight in recent years given their implication in a myriad of cellular and developmental processes. Despite their recognized importance and intense study, there are still many open questions about their biogenesis and function. In the present article, we review the existing(More)
The formation of the mitotic spindle is a complex process that requires massive cellular reorganization. Regulation by mitotic kinases controls this entire process. One of these mitotic controllers is Aurora A kinase, which is itself highly regulated. In this study, we show that the nuclear pore protein ALADIN is a novel spatial regulator of Aurora A.(More)
PHD1 (also known as EGLN2) belongs to a family of prolyl hydroxylases (PHDs) that are involved in the control of the cellular response to hypoxia. PHD1 is also able to regulate mitotic progression through the regulation of the crucial centrosomal protein Cep192, establishing a link between the oxygen-sensing and the cell cycle machinery. Here, we(More)
  • A Badran, President, +497 authors A Mexico Muhammed
  • 2009
• A sample of opinions on the EOLSS project • EOLSS-online ( Subscription Rates 1.2. DESWARE: Encyclopedia of Desalination and Water Resources, for details visit ( 2. EOLSS e-books and hard copy publications in the following subject categories • Prices of e-books and print volume DISCLAIMER The information, ideas, and opinions(More)
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