Sara Brandi Bloch

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PURPOSE To assess baseline and follow-up characteristics of choroidal neovascularization (CNV) lesions in age-related macular degeneration in relation to the development of subfoveal subretinal fibrosis. DESIGN Retrospective, observational case series. METHODS settings and study population: One hundred ninety-seven treatment-naïve eyes in 197 patients(More)
PURPOSE To report incidence rates of legal blindness from age-related macular degeneration (AMD) and other causes in Denmark from years 2000 to 2010 in the age group at risk of AMD aged 50 years and older. DESIGN Population-based observational registry study. METHODS settings: Membership register of the Danish Association of the Blind, the primary(More)
OBJECTIVE To investigate the visual outcome, pattern of discontinuation, ocular complications, and mortality of patients treated with a variable ranibizumab dosing regimen for neovascular age-related macular degeneration (AMD) for 4 years. DESIGN Retrospective chart review supplemented with clinical examination. PARTICIPANTS Six hundred eyes of 555(More)
PURPOSE To describe predictors of visual outcome in patients treated with intravitreal ranibizumab for choroidal neovascularisation (CNV) in age-related macular degeneration (AMD). METHODS Retrospective review of 279 patients with CNV in AMD who fulfilled MARINA/ANCHOR study eligibility criteria and were treated with repeated intravitreal injections of(More)
The pathogenesis of AMD is associated with age changes plus pathological changes involving oxidative stress and an altered inflammatory response leading to injury of retinal pigment epithelial cells and the adjacent choroidea and photoreceptor cells. AMD is divided into early, intermediate and advanced AMD. The advanced form of AMD is further divided into(More)
PURPOSE To evaluate and to compare the safety of intravitreal ranibizumab injections performed by physicians and nurses at a single large hospital clinic in Denmark during 5 years. DESIGN Retrospective, interventional, non-comparative study. METHODS SETTING All eyes that underwent a protocolized ranibizumab injection procedure performed in an(More)