Sara Brachi

Learn More
Hypocalcemia due to hypoparathyroidism (HPT) is a late complication of iron-overloaded patients with b-thalassaemia major (TM). The majority of patients have mild disease with parasthesias, while in the more severe form tetany, seizures or cardiac failure may occur. In the last 20 years we observed heart failure in 2 out of 38 (5.2%) TM patients (aged 18(More)
Since the introduction of hypertransfusion and intensive iron chelation therapy, patients with homozygous beta-thalassaemia major (TM) achieve adulthood. Many patients grow and develop normal hoping for marriage and to have a family. Therefore the question of fertility potential in this adult group of TM patients has become paramount. We report the semen(More)
Extramedullary haematopoiesis (EH) refers to the production of blood cells outside the bone marrow as a compensatory mechanism for bone marrow dysfunction. It occurs in conditions with hyperactive, depleted or infiltrated marrow. The most frequent cause of EH is thalassaemia intermedia, due to increased demand on the hematopoietic system from anemia not(More)
Introduction Antinuclear antibodies (ANA) are frequently found in children with connective tissue diseases but can be also found in healthy individuals even in absence of autoimmune conditions, with a prevalence ranging from 13.3% (titer ≥1:80) to 5.0% (titer ≥1:160). Puberty is a period of important changing in immune system because of the sexual and(More)
The Authors have examined the results of 14.703 colposcopic examinations performed at the Social Medicine Center of the Province of Florence between 1974 and 1978, grouping the women according to childbearing and age. The purpose was to verify if mechanical and traumatic factors related to delivery may be responsible for modifications of the epithelial(More)
Introduction Chronic Musculoskeletal Pain (MSP) in children can be due to various non-inflammatory conditions, such as the benign joint hypermobility syndrome (BJHS) or idiopathic MSP (IMSP). MSP heavily influences patient’s quality of life and is often misdiagnosed or included in the vast category of unspecific MSP. A careful differential diagnosis and(More)
BACKGROUND Chronic Musculoskeletal Pain (MSP) in children can be due to non-inflammatory conditions, such as the benign joint hypermobility syndrome (BJHS) or idiopathic MSP (IMSP). Aim of the study was to evaluate type and persistence of MSP in a cohort of schoolchildren with MSP followed for 3 years, in order to identify the main risk factors. METHODS(More)