Sara A. Moura-Tamames

  • Citations Per Year
Learn More
Glycoside hydrolases are a class of enzymes that break/form the bond between sugar monomers (monosaccharides). Candida albicans's beta-1,3-exoglucanase (Exg), a family 5 glycosidase, belongs to this class of enzymes. This small protein is an ideal computational model for its family of enzymes and was used here to create several enzyme-substrate models(More)
Glycoside hydrolases catalyze the breaking of the glycosidic bond. This type of bond fashioned between two monosaccharides is very stable, and the polymers created are involved in multiple cellular processes, being crucial to life. In this article, computational methods were used to study the first step of the mechanism of reaction of retaining glycoside(More)
  • 1