Sara A. Karlsson

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Development of breast cancer is a multistage process influenced by hormonal and environmental factors as well as by genetic background. The search for genes underlying this malignancy has recently been highly productive, but the etiology behind this complex disease is still not understood. In studies using animal cancer models, heterogeneity of the genetic(More)
Autism spectrum disorders (ASDs) are more prevalent in boys than in girls, indicating that high levels of testosterone during early development may be a risk factor. Evidence for this hypothesis comes from studies showing associations between fetal testosterone levels, as well as indirect measures of prenatal androgenization, and ASDs and autistic-like(More)
The role of sex and androgen receptors (ARs) for social preference and social memory is rather unknown. In this study of mice we compared males, females and males lacking ARs specifically in the nervous system, AR(NesDel), with respect to social preference, assessed with the three-chambered apparatus test, and social recognition, assessed with the social(More)
The ability to recognize the identity of faces and voices is essential for social relationships. Although the heritability of social memory is high, knowledge about the contributing genes is sparse. Since sex differences and rodent studies support an influence of estrogens and androgens on social memory, polymorphisms in the estrogen and androgen receptor(More)
BACKGROUND It is well-established that organizational effects of sex steroids during early development are fundamental for sex-typical displays of, for example, mating and aggressive behaviors in rodents and other species. Male and female brains are known to differ with respect to neuronal morphology in particular regions of the brain, including the number(More)
In this thesis, contemporary universities and their response to external pressure are studied. The term " the active university " is put forward as an analytical tool. The active university " acts " in two ways: by taking concrete initiatives and by playing a role. The concept is inspired by theories on strategic actorhood and by new institutional theory.(More)
Westberg. Effects of sex and gonadectomy on social investigation and social recognition in mice. androgen receptors modulate gene expression and social recognition but not social investigation. analyses of limbic regions in neonatal male, female and androgen receptor knockout mice. Submitted. Lars Westberg. Social memory associated with estrogen receptor(More)
An individual’s ability to recognise and pay attention to others is crucial in order to behave appropriately in various social situations. Studies in humans have shown a sex bias in sociability as well as social memory, indicating that females have better face memory and gaze more at the eyes of others, but information about the factors that underpin these(More)
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