Santos Gomes Ferreira

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Recently, we showed expression of apolipoprotein E (apoE) in human neuronal-type cells such as neuroblastoma SK N SH-SY 5Y cells. In this model, a negative effect of neuronal differentiation on apoE synthesis was suspected. To check this hypothesis, we studied the regulation of apoE in human postmitotic neurons. The presence of apoE was investigated in(More)
Today, there is an increasing need to analyse very large datasets, that have been coined “big data”, and that require specialised storage and processing infrastructures. MapReduce is a programming model aimed at processing big data in a parallel and distributed manner. Known for its scalability, ease of use and fault-tolerance, MapReduce has been widely(More)
As I began writing this proposal, serendipity struck in the form of two conversations about Open Educational Resources (OERs), one with a colleague in my own institution who has a respectable track record in innovative uses of educational technologies, another with a freelance learning facilitator engaged in full-time voluntary work. ‘Without a teacher,(More)
Acid azo dyes, most of them naphtholdisulfonic acid derivatives, were given intraperitoneally to rats and their effect on "alkaline" ribonuclease activity was studied in total homogenates of kidney cortex and liver. Acid treatment was used to release bound enzyme activity. Several of the dyes, including trypan blue, increased RNase activity in both organs 3(More)
Acid azo dyes, most of them naphtholdisulfonic acid derivatives, were given intraperitoneally to rats and their effect on "alkaline" ribonuclease activity was studied in total homogenates of kidney cortex and liver. Acid treatment was used to release bound enzyme activity. Several of the dyes, including trypan blue, increased RNase activity in both organs 3(More)
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