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  • Charles L. Sawyers, A. Hochhaus, +28 authors Brian J. Druker
  • Medicine
  • Blood
  • 2002 (First Publication: 15 May 2002)
  • Blast crisis is the most advanced stage of chronic myelogenous leukemia (CML) and is highly refractory to therapy. CML is caused by expression of the chimeric BCR-ABL tyrosine kinase oncogene, theContinue Reading
  • Moshe Talpaz, Richard T. Silver, +19 authors Charles L. Sawyers
  • Medicine
  • Blood
  • 2002 (First Publication: 15 March 2002)
  • Chronic myelogenous leukemia (CML) is caused by expression of the BCR-ABL tyrosine kinase oncogene, the product of the t(9;22) Philadelphia translocation. Patients with CML in accelerated phase haveContinue Reading
  • Richard T. Silver, Steven H. Woolf, +9 authors Sante Tura
  • Medicine
  • Blood
  • 1999 (First Publication: 1 September 1999)
  • Because there are differing opinions regarding treatment of patients in the chronic phase of chronic myeloid leukemia (CML), the American Society of Hematology convened an expert panel to review andContinue Reading
  • Michele Cavo, Elena Zamagni, +12 authors Michele Baccarani
  • Medicine
  • Blood
  • 2005 (First Publication: 1 July 2005)
  • The aim of the present study was to compare thalidomide-dexamethasone (Thal-Dex) and vincristine-doxorubicin-dexamethasone (VAD) as primary therapy in preparation for autologous peripheral bloodContinue Reading
  • Tiziano Barbui, Giovanni Barosi, +6 authors Sante Tura
  • Medicine
  • Haematologica
  • 2004
  • BACKGROUND AND OBJECTIVES The Italian Society of Hematology (SIE) and the two affiliated Societies (SIES and GITMO) commissioned a project to develop guidelines for the therapy of essentialContinue Reading